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Prokar Dasgupta ABC of Prostate Cancer


Prostate cancer is the most common cancer in men in the UK and US and the second most common worldwide. The ABC of Prostate Cancer provides fully illustrated guidance on the treatment and management of prostate cancer. It covers the biology, anatomy, and pathology of prostate cancer, screening, and active surveillance and monitoring. It presents an assessment of treatment options including prostatectomy, bracytherapy, chemotherapy and immunotherapy, along with modern diagnostic tests and an overview of new approaches to prostate cancer. With an international author team, the ABC of Prostate Cancer is ideal for general practitioners, family physicians, specialist nurses, junior doctors, medical students and others working with prostate cancer patients and their families.

3166.26 RUR

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Ian Hunt ABC of Lung Cancer


Lung Cancer is the most common cause of cancer death and cancer symptoms. The ABC of Lung Cancer is a much needed reference for those treating and caring for patients with lung cancer such as primary care doctors, specialist cancer nurses, junior doctors, nurses, physiotherapists, radiographers and other health care professionals. This new title in the ABC series covers the epidemiology and diagnosis of lung cancer, focusing particularly on primary care issues such as what symptoms require urgent investigation, and when to refer to a specialist. This is a practical guide for all those involved in the care of the lung cancer patient, as well as patients and their families and carers.

3707.66 RUR

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Peter Whelan Prostate Cancer. Diagnosis and Clinical Management


Do you manage patients with prostate cancer? Could you use an expert guide examining all possible management options? Prostate Cancer: diagnosis and clinical management providesurologists and oncologists of all levels with up-to-date, evidence-based guidance to the diagnosis, treatment and clinical management of a disease which accounts for a quarter of all cancers affecting men. Designed to be as practical and accessible as possible, leading experts discuss key issues in prostate cancer management and examine how to deliver best practice in the clinical care of their patients. Topics covered include: What must be considered when counseling newly-diagnosed cancer patients Radical surgery options for prostate cancer Novel therapies for localized prostate cancer How should metastatic prostate cancer be diagnostic and managed What are the best methods of administering end of life care for the patient Brought to you by a highly experienced editor team, and containing key points, management algorithms, practice tips and the latest AUA and EAU clinical guidelines, this is the ideal consultation tool for doctors both on the wards and in the office.

8269.99 RUR

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Richard Hobbs ABC of Colorectal Cancer


Colorectal cancer is a common cause of morbidity and mortality in which prevention, screening and early detection are vital. Beginning with the patient perspective and following the patient pathway, this new second edition covers epidemiology and prevention, screening programmes, decision support networks, the role of primary care, and supportive care for patients with colorectal cancer. The ABC of Colorectal Cancer provides the core knowledge on clinical genetics, diagnosis, imaging, therapy and surgery options and the latest evidence based guidelines for treating and managing colorectal cancer patients within the multidisciplinary team. Highly illustrated and accessible, it covers the full spectrum of the disease to provide the basis to make a real difference to clinical management. This is an invaluable practical guide for the non-specialist on all aspects of colorectal cancer, and is ideal for general practitioners, junior doctors, nurses and allied health professionals.

2702.62 RUR

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Manit Arya Focal Therapy in Prostate Cancer


This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer.

11053.3 RUR

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Carlo Palmieri ABC of Cancer Care


ABC of Cancer Care is a practical primary care guide to help health professionals better inform their patients, manage and recognize the common complications of cancers and their treatment, and understand the rationale and implications of decisions made in secondary and tertiary care. It provides coverage of the diagnosis, management, treatment and on-going surveillance of common cancers within the multidisciplinary context of primary care. Individual chapters assess the different treatment options, including surgery, radiotherapy and chemotherapy, and examine their possible side effects. The contribution of clinical trials and new advances in cancer treatment including biological and targeted therapies, robotic surgery and advanced radiotherapy techniques are all described. Other aspects of cancer care, from nursing support and nutrition to psychological care and survivorship, are also covered. Edited by a specialist and general practitioner team, with multidisciplinary contributors, ABC of Cancer Care is ideal for general practitioners, practice nurses, cancer care nurses, medical students, and all healthcare professionals treating and supporting cancer patients. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

2780.38 RUR

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Dawson Chris ABC of Urology


The ABC of Urology provides a comprehensive review of current practice in urology and is a structured and practical guide to the diagnosis, treatment and management of the most common urological conditions. This new third edition has been fully revised and expanded with additional chapters and improved coverage of renal and testis cancer, management of haematuria, laparoscopy, trauma and new urological advances. Prostate, bladder, renal and penile cancers are also covered in detail and new techniques and procedures for safer and effective treatment options are featured. The ABC of Urology is the ideal reference for general practitioners and general practitioner trainees, junior doctors and practice nurses, medical students and all primary health care professionals working to provide the best possible care for patients with urological conditions.

3177.85 RUR

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Jacques Robert ABC Transporters and Multidrug Resistance


A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs. ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance. This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.

12372.33 RUR

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Bone Cancer: Primary Cancers and Metastases


Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials.Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases - from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.- Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one referenc...

9060 RUR

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J. Dixon Michael ABC of Breast Diseases


The ABC of Breast Diseases provides comprehensive guidance to the assessment of symptoms, and how to manage all common breast conditions and provides guidelines on referral. It covers congenital problems, breast infection and mastalgia, before addressing the epidemiology, prevention, screening and diagnosis of breast cancer. It outlines the treatment and management options for breast cancer within different groups and includes new chapters on the genetics, prevention, management of high risk women and the psychological aspects of breast diseases. Edited and written by internationally renowned experts in the field and highly illustrated in full colour, this fourth edition remains a practical guide for general practitioners, family physicians, practice nurses and breast care nurses as well as for surgeons and oncologists both in training and recently qualified as well as medical students.

3876.28 RUR

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Gosney Margot Cancer and Aging Handbook. Research Practice


A state-of-the-art, multidisciplinary approach to cancer and aging With the majority of cancers occurring in individuals over the age of 65 against a backdrop of an expanding aging population, there is an urgent need to integrate the areas of clinical oncology and geriatric care. This timely work tackles these issues head-on, presenting a truly multidisciplinary and international perspective on cancer and aging from world-renowned experts in geriatrics, oncology, behavioral science, psychology, gerontology, and public health. Unlike other books on geriatric oncology that focus mainly on treatment, Cancer and Aging Handbook: Research and Practice examines all phases of the cancer care continuum, from prevention through evidence-based diagnosis and treatment to end-of-life care. Detailed clinical and research information helps guide readers on effective patient care as well as caregiver training, research, and intervention. Coverage includes: Epidemiology of cancer in older adults, plus the unique physical, mental, and social issues involved Strategies and guidelines for prevention, screening, and treatment of older individuals with cancer The most common cancers in the elderly, including breast, colorectal, lung, prostate, and ovarian cancer Cancer survivorship in older adults as well as the all-critical issues of palliative care and pain management Emerging topics such as caregiver and family issues, different models of care, and cost considerations An essential resource for clinicians and caregivers as well as researchers interested in this evolving field, Cancer and Aging Handbook is also useful for public health professionals and policymakers who need to formulate services and allocate resources for the growing population of older cancer patients.

11093.39 RUR

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Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals


Over 99% of the world's population is infected with at least one potentially cancer-causing organism. It is vital for nurses and other healthcare professionals to be aware of the extent of infection-associated cancer and of how they can contribute to prevention of such cancers. Infectious Causes of Cancer, aimed principally at nurses and other healthcare professionals, considers the epidemiology and biology of infectious causes of cancer. It examines each of the infectious agents associated with an increased risk of cancer, discussing epidemiology of the infection and cancer, pathophysiology of the cancer, mechanisms, associated risk factors, and prevention of the infection and cancer. Key Features: A comprehensive and accessible guide to infection associated cancer and how to contribute to prevention A must-have for students or healthcare professionals working in oncology, primary care or health promotion Brings together all the up-to-date science, evidence and research related to infections and cancer in one publication

5742 RUR

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Maurie Markman Cancer Nutrition and Recipes For Dummies


Fight cancer from the inside out Cancer treatments such as surgery, chemotherapy, and radiation can be as hard on the body as the disease itself, and detailed nutritional advice is usually not part of the program. Yet eating the right foods can actually help lessen the strength of some of the most powerful symptoms of cancer and the side effects of treatment, allowing the patient to better fight the disease. Now, Cancer Nutrition & Recipes For Dummies is your trusted, informative guide to fighting cancer from the inside out. Designed for cancer patients and their families, Cancer Nutrition & Recipes For Dummies focuses on foods best tolerated during—and that can ease side effects of—cancer treatment. It also offers advice for menu planning, nutritional analysis, diabetic exchanges, and much more. Serves as a guide for cancer nutrition before, during, and after treatment Gives you a wealth of easy, immediate steps to speed up the healing process through diet Offers advice on treatment as well as solutions to common side effects like dehydration, fatigue, and nausea Enables cancer patients to put their strongest foot forward when starting treatment Cancer Nutrition & Recipes For Dummies targets those dealing with cancer and the loved ones who take care of them, aiding both parties in alleviating some of the side effects of the cancer treatment through change in diet.

1486.75 RUR

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Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications Therapeutics


Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

11594.71 RUR

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Antonio Giordano Cancer Epigenetics. Biomolecular Therapeutics in Human


Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and aims to facilitate collaboration between the basic, translational, and clinical sciences.

12754.54 RUR

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Joy Ogden Understanding Breast Cancer


Two decades ago, a diagnosis of breast cancer meant only one thing: mastectomy. A revolution in treatment has given those now afflicted a choice of treatment options far beyond this draconian cure-all. Written by a noted health journalist and former patient, Understanding Breast Cancer offers reliable, up-to-date information on today's most effective treatments. With insights and advice from breast cancer patients who experienced different diagnoses and levels of treatment, Joy Ogden candidly shows how an informed and proactive approach can turn a cancer patient into one of a legion of cancer survivors.

1548.19 RUR

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A. Truswell Stewart ABC of Nutrition


This well established ABC has been updated with new charts, illustrations and guidelines on aspects of nutrition which affect heart disease, blood pressure, chronic diseases such as diabetes and some types of cancer. The book also contains the most current nutritional recommendations for pregnancy and infant feeding as well as advice for children and adults young and old. With chapters covering nutritional deficiencies in both developing and affluent countries as well as eating disorders and obesity, this latest edition has worldwide relevance.

4109.09 RUR

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Bailey Christopher D. Cancer Nursing. Care in Context


The needs of cancer patients and their families are complex. Yet still more complex are the powerful social and cultural forces that shape the delivery of cancer care, and the way in which it experienced. Cancer Nursing: Care in Context addresses this by adopting a unique approach that situates cancer care in the context of society‘s attitudes to the disease, and the broader every-day needs of both patients and their carers. By combining evidenced-based information, a critical view of care and treatment, and ‘first-hand accounts’ of having cancer and caring for people with cancer, the book provides a new perspective how best to deliver the care that patients truly require. This second edition includes new chapters on prevention, diagnosis, symptoms, self-help and self-management, and living with cancer long-term. It also: • Addresses significant changes in cancer care, including expansion of nursing roles, the establishment of cancer networks and cancer collaborative projects • Considers NICE guidance on Supportive and Palliative care • Incorporates material on prevention and early detection • Includes evidence tables based on relevant literature Cancer Nursing: Care in Context is an invaluable resource for all those involved in the provision of cancer care and support to patients and their families.

8147.7 RUR

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Sharmila Bapat A. Cancer Stem Cells. Identification and Targets


Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology – two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.

8532.48 RUR

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Norman Sartorius Depression and Cancer


Recently, there has been a growing awareness of the multiple interrelationships between depression and cancer. Depression and Cancer is devoted to the interaction between these disorders. The book examines various aspects of this comorbidity and describes how the negative consequences of depression in cancer could be avoided or ameliorated, given that effective depression treatments for cancer patients are available. Renowned psychiatrists and oncologists summarize the latest evidence on the epidemiology, pathogenesis, screening and recognition, and cultural and public health implications of depression in persons with cancer, among other topics.

4715.65 RUR

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Bartley Trish Mindfulness-Based Cognitive Therapy for Cancer. Gently Turning Towards


Mindfulness-based Cognitive Therapy for Cancer presents an eight-week course for MBCT which has been tried and tested over ten years of clinical use, and is targeted specifically for people with cancer. There is growing evidence of mindfulness as a successful and cost-effective intervention for reducing the negative psychological impact of cancer and treatment Draws upon the author’s experience of working with people with cancer, and her own recent experience of using mindfulness with cancer diagnosis and treatment Stories from cancer patients illustrate the learning and key themes of the course Includes new short practices and group processes developed by the author

9075.7 RUR

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Vinagolu Rajasekhar K. Cancer Stem Cells


Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.

14895.95 RUR

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Rosalind Eeles A. Cancer Prevention and Screening. Concepts, Principles Controversies


Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques

9696.53 RUR

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Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy


Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive – and how they can be turned into potent weapons against it – is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.

6185.8 RUR

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Jack Roth A. Lung Cancer


The best and most concise single source for state-of-the-art diagnosis and treatment of lung cancer –newly revised, updated, and expanded. Lung cancer has long been the number-one cause of death from cancer every year and the third most frequently diagnosed after breast and prostate cancers. In 2010, about 15% of all cancer diagnoses and 30% of all cancer deaths were due to lung cancer. Needless to say, there is a great need for more rapid advancements in diagnosis and treatment of this devastating disease. Here is the comprehensively revised, updated, and expanded edition of the well-established, evidence-based reference book that deals with the most recent advances in lung cancer prevention, screening, diagnosis, research, and treatment for the clinician. Edited and authored by leading authorities in the field, this Fourth Edition of the highly regarded Lung Cancer is better than ever –featuring nine new chapters along with seven re-formatted ones that are nearly brand new in content and approach. It covers Smoking Prevention and Cessation; Molecular Profiling; Somatic Genome Alterations in Human Lung Cancers; Management of Multi-Focal Bronchioloalveolar Carcinoma (BAC); Primary Tracheal Tumors; Predictive Tumor Biomarkers for EGFR Inhibitors; Non-Small Cell and Small-Cell Lung Carcinoma; and more. This Fourth Edition of Lung Cancer: Provides the very latest research in the identification of biomarkers to predict a high risk for developing lung cancer – vital for implementing screening, diagnosis, and prevention strategies Presents the newest lung cancer staging system, as well as updated and cutting-edge surgical and radiation therapy techniques that make local tumor control more effective and less invasive while sparing normal tissues Discusses combined modality therapy and new chemotherapeutic agents which are yielding higher response rates and improved survival when used in the adjuvant setting or concurrent with highly sophisticated radiation or proton treatment Offers novel and emergent approaches to preventative, diagnostic, and therapeutic modalities with an emphasis on the best evidence available from the latest studies and clinical trials With almost half of the revised and updated content being brand new, Lung Cancer, Fourth Edition, is an important and vital resource for all medical professionals and students involved in the care and treatment of those struck with this catastrophic illness.

14378.76 RUR

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Stella Pelengaris The Molecular Biology of Cancer. A Bridge from Bench to Bedside


The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. “Bench to Bedside”: A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients – essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: An overview of the cancer cell and important new concepts. Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. Chapters highlighting the direct links between cancer research and clinical applications. New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Quotations have been used in each chapter to introduce basic concepts in an entertaining way. Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: “A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology…..This book deserves great praise for the readable presentation of this complex field….the true synthesis of bench and bedside approaches is marvelously achieved.” Christian Schmidt, Molecular Cell “Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references….This book is applicable to both graduate and undergraduate students, and in the context of a

12372.33 RUR

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Martine Piccart-Gebhart Holland-Frei Cancer Medicine


Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

23193.08 RUR

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Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors


Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.

11981.32 RUR

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Daniels Ron ABC of Sepsis


The importance of early prevention and treatment of sepsis has never been greater. In the UK alone sepsis contributes to more deaths than lung cancer, from bowel cancer and breast cancer combined, and approximately one third of patients who suffer from severe sepsis die. The ABC of Sepsis provides a much needed introduction and an invaluable aid in the increasing efforts to reduce hospital infection and improve patient safety. As growing numbers of junior medical staff experience emergency medicine, critical care and acute medicine as part of the Foundation Programme, there is an increasing need to develop the skills required to treat severe sepsis. The editors are involved with the Survive Sepsis campaign – developed to improve the recognition, diagnosis and treatment of sepsis – and are perfectly placed to guide junior medics, GPs, specialist nurses, critical care nurses and primary care staff through this core aspect of acute medicine.

4574.71 RUR

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McQueen Anne Perspectives on Cancer Care


Perspectives on Cancer Care is a unique collection of insights from contributors, based on their specific expertise and experience. It provides a range of perspectives on cancer care to inspire readers and encourage high-quality care through an enhanced understanding of patients' needs and carers' skills. The book presents a series of chapters highlighting different circumstances and approaches to the complex reality of cancer care. In each chapter the author presents their own picture of their experience of the individual's needs and the care required to address these needs, illustrating the particular sensitivity, trust, empathy and support required in the care of patients with cancer and their families. The holistic approach to total care is a prominent feature in cancer care and this is illustrated throughout the various chapters. This collection of perspectives on cancer care: highlights particular issues in the field encourages best practice draws on the expertise of specialist practitioners in the field of cancer care features a holistic approach to cancer care, illustrated through scenarios

4189.93 RUR

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Jeang Kuan-Teh Viral Oncology. Basic Science and Clinical Applications


A comprehensive look at the latest research findings and clinical applications of oncogenic viruses Written by a panel of academic experts, Viral Oncology is the first self-contained and comprehensive book to present both scientific and clinical information on viruses linked to some of the most important human cancers. Readers can turn to this book for the most in-depth and up-to-date coverage of: HPV-associated cancers; molecular events associated with HPV-induced human cancer; the role of the HPV E6 oncoprotein in malignant progression; virus association with brain tumors; involvement of the polyomavirus JCV in colorectal cancer; possibleassociation of BKV with prostate cancer; oncogenic transformation bypolyomavirus large T antigen; SV40 and human cancer; SV40 and mesothelioma; molecular immunology of hepatitis B–associated viral cancer; hepatitis B vaccine and hepatocellular carcinoma; pathogenesis of acute and chronic hepatitis Cvirus infection; molecular mechanisms of hepatitis C virus-induced cellulartransformation; clinical aspects of HTLV-1 associated cancer; oncogenic potential of the HTLV-1 tax protein; HIV-associated malignancy; HIV-related lymphoma; biology and epidemiology of HHV-8; the role of KSHV in pathogenesis of Kaposi'ssarcoma; molecular pathobiology of EBV infection; and EBV as a pathogen. Several chapters are devoted to the basic science of oncogenic viruses for thestudy of their pathogenesis, drug development, and employment of viral vectorsfor vaccine and gene therapy. The book also includes complementary clinically based chapters describing natural courses and treatments. Additionally, bonusclinical materials are embedded within chapters and an easy-to-use indexcompletes the book. Viral Oncology is an essential resource for clinical and research oncologists in medical facilities and biological research laboratories; clinicians and scientists working in related biomedical areas; medical students working toward a first or higher degree in the life sciences and other biomedical fields; and pharmaceutical scientists and developers.

14818.35 RUR

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Alison Leary Lung Cancer. A Multidisciplinary Approach


Lung Cancer: A Multidisciplinary Approach provides clinicians with a comprehensive text that can be used when caring for patients with lung cancer throughout the entire patient journey. This edited collection explores the aetiology of lung cancer; mesothelioma; the range of available treatments, including chemotherapy and radiotherapy; surgical care; supportive and end-of-life care; quality-of-life issues; and the role of the nurse within the multidisciplinary team. A comprehensive, evidence-based guide to lung cancer Illustrative case studies used throughout Contributions from respected healthcare professionals in the field Interprofessional in focus Lung Cancer: A Multidisciplinary Approach is an essential resource for all nurses and healthcare professionals working with cancer patients.

2169.01 RUR

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Alison Leary Lung Cancer. A Multidisciplinary Approach


Lung Cancer: A Multidisciplinary Approach provides clinicians with a comprehensive text that can be used when caring for patients with lung cancer throughout the entire patient journey. This edited collection explores the aetiology of lung cancer; mesothelioma; the range of available treatments, including chemotherapy and radiotherapy; surgical care; supportive and end-of-life care; quality-of-life issues; and the role of the nurse within the multidisciplinary team. A comprehensive, evidence-based guide to lung cancer Illustrative case studies used throughout Contributions from respected healthcare professionals in the field Interprofessional in focus Lung Cancer: A Multidisciplinary Approach is an essential resource for all nurses and healthcare professionals working with cancer patients.

4252 RUR

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